Juvenile Hereditary Cataract

Various types of hereditary cataracts in dogs varying in appearance and age of onset. Most of them are autosomal recessive traits, but some are inherited in a dominant or polygenic traits.

Recently, the research group of Dr. Cathryn Mellersh at the Animal Health Trust has identified a mutation in the HSF4 gene responsible for recessive hereditary juvenile cataracts in Staffordshire Bull Terriers and Boston Terriers.

Importantly, the Boston Terrier breed there are two types of cataracts: cataract of early onset (early onset cataract - EHC), also known as juvenile hereditary cataract, cataract and late onset (late onset - LHC). This test is relevant only to the first. The Boston Terrier hereditary juvenile cataract (EHC) progresses to a complete cataract and blindness at 2-3 years of age, and late cataract (LHC) occasionally interfere with vision and is detected before 8 years of age. Staffordshire Bull Terrier in the EHC is detected by 12 months and progresses to blindness by 3 years of age.
Boston Terrier
Staffordshire Bull Terrier


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